The process of developing new mesothelioma drugs.
The Department of Veterans Affairs and the National Cancer Institute have an agreement to increase access of eligible veterans to all phases of NCI-sponsored prevention, diagnostic and treatment clinical trial.
The Community Clinical Oncology Program (CCOP) is a nationwide network that ensures that cancer patients have access to medical care in their own communities
I accidentally went through this site and it kept me there for long searching most of its pages.They have the full information,yes they have.They will tell you the treatment and have other options for this disease like surgery and more.This is the best site i have ever seen online.
This site has got full information on mesothelioma lawyer which is bit difficult to get in other sites.They have a form to fill up so that you get a book in very short time to cure this disase.A best place to see.You wont regret it.This site has got a big list of mesothelioma lawyers for your service at any place in u.s.
This site will get you to mesothelioma attorney for the process.They have the best people to work with and its a great place.You will come to know that when you check this site.Iam really happy to see a site with all these informatio.
An easy to use site with out any complication makes this site more popular.Anyone can use this site with ease.If you want to know the
Friday, May 8, 2009
GOOD NEWS FOR MESOTHELIOMA
i have come through a beautiful site about mesothelioma.a place where you will get more details about the disease, treatment and more. I accidentally went through this site and it kept me there for long searching most of its pages.They have the full information,yes they have.They will tell you the treatment and have other options for this disease like surgery and more.This is the best site i have ever seen online.
This site has got full information on mesothelioma lawyer which is bit difficult to get in other sites.They have a form to fill up so that you get a book in very short time to cure this disase.A best place to see.You wont regret it.This site has got a big list of mesothelioma lawyers for your service at any place in u.s.
This site will get you to mesothelioma attorney for the process.They have the best people to work with and its a great place.You will come to know that when you check this site.Iam really happy to see a site with all these informatio.
An easy to use site with out any complication makes this site more popular.Anyone can use this site with ease.If you want to know the latest news on mesothelioma then they have news place where you get the latest news on this disease.
A must to see site with all you need for a mesothelioma disease.
This site has got full information on mesothelioma lawyer which is bit difficult to get in other sites.They have a form to fill up so that you get a book in very short time to cure this disase.A best place to see.You wont regret it.This site has got a big list of mesothelioma lawyers for your service at any place in u.s.
This site will get you to mesothelioma attorney for the process.They have the best people to work with and its a great place.You will come to know that when you check this site.Iam really happy to see a site with all these informatio.
An easy to use site with out any complication makes this site more popular.Anyone can use this site with ease.If you want to know the latest news on mesothelioma then they have news place where you get the latest news on this disease.
A must to see site with all you need for a mesothelioma disease.
GOOD NEWS FOR MESOTHELIOMA treatment
mesothellioma:i have come through a beautiful site about mesothelioma.a place where
At present, the following trials are actively testing new drugs or treatments for mesothelioma. They are listed by title with a short description and have no particular order or endorsement.
National Institutes of Health (NIH) Clinical Center, Bethesda, MD
The Informed Consent process for patients in clinical trials.
Investigational drugs are those under evaluation in the clinical trial system, but not yet approved by the Food and Drug Administration to be legally marketed and sold. More on investigational drugs.
The process of developing new mesothelioma drugs.
The Department of Veterans Affairs and the National Cancer Institute have an agreement to increase access of eligible veterans to all phases of NCI-sponsored prevention, diagnostic and treatment clinical trial.
The Community Clinical Oncology Program (CCOP) is a nationwide network that ensures that cancer patients have access to medical care in their own communities
MESOTHELIOMA CANCER -CLINICAL TRAILS
MESOTHELIOMA
it,s a rare and severe type of cancer. the treatments available are not effective in treating disease.
This also arises partly from the fact that the disease is not well known. New methods and procedures need to be developed in order to improve the effectiveness of the treatment. Clinical trials are studies directed for the purpose to develop new treatments and to evaluate the effectiveness and safety of these new treatments.
There are basically four phases in a clinical trial and each phase has its goals. The phases are as follows:
Phase 1: This phase studies the safety and side effects of a new drug. It tries to determine the best way that this new drug is administered and tries to determine the appropriate dosage. It is important to state that not only new drugs are studied in a clinical trial but treatments such as surgery, radiation therapy and other treatments may also be studied. Before any treatment is tested on humans it has been already tested in the laboratory, usually on animals, but its side effects on humans will not accurately be determined until it is actually tested on them.
Phase 2: In this phase the treatment's effectiveness to fight mesothelioma will be studied and the treatment's safety will further be evaluated.
Phase 3: the new treatment is compared to existing treatments in order to study side effects and confirm its effectiveness.
Phase 4: Information is gathered in order to determine how an already approved treatment can be used to treat other diseases.
To be eligible for a clinical trial the patient should have certain characteristics. Eligibility depends on the stage of the disease, the age of the individual and many other factors. There are different types of clinical trials and eligibility is not the same for all. There is no guarantee that a clinical trial will produce the desired results. Further more the patient is obviously exposed to certain risks. Therefore it is very important that the patient talks with his physician and is well informed about the advantages and risks involved and the adequacy of clinical trial in his or her particular situation.
For more info go to Mesothelioma Cancer
it,s a rare and severe type of cancer. the treatments available are not effective in treating disease.
This also arises partly from the fact that the disease is not well known. New methods and procedures need to be developed in order to improve the effectiveness of the treatment. Clinical trials are studies directed for the purpose to develop new treatments and to evaluate the effectiveness and safety of these new treatments.
There are basically four phases in a clinical trial and each phase has its goals. The phases are as follows:
Phase 1: This phase studies the safety and side effects of a new drug. It tries to determine the best way that this new drug is administered and tries to determine the appropriate dosage. It is important to state that not only new drugs are studied in a clinical trial but treatments such as surgery, radiation therapy and other treatments may also be studied. Before any treatment is tested on humans it has been already tested in the laboratory, usually on animals, but its side effects on humans will not accurately be determined until it is actually tested on them.
Phase 2: In this phase the treatment's effectiveness to fight mesothelioma will be studied and the treatment's safety will further be evaluated.
Phase 3: the new treatment is compared to existing treatments in order to study side effects and confirm its effectiveness.
Phase 4: Information is gathered in order to determine how an already approved treatment can be used to treat other diseases.
To be eligible for a clinical trial the patient should have certain characteristics. Eligibility depends on the stage of the disease, the age of the individual and many other factors. There are different types of clinical trials and eligibility is not the same for all. There is no guarantee that a clinical trial will produce the desired results. Further more the patient is obviously exposed to certain risks. Therefore it is very important that the patient talks with his physician and is well informed about the advantages and risks involved and the adequacy of clinical trial in his or her particular situation.
For more info go to Mesothelioma Cancer
SIGNS AND SYMPTOMS
symptoms of mesothelioma may not appear untill 20 to 50 years after exposure to asbestors. softness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space are often symptoms to pleural mesothelioma.
Symptoms of peritoneal mesothelioma include weight loss and cachexia, abdominal swelling and pain due to ascites (a buildup of fluid in the abdominal cavity). Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.
These symptoms may be caused by mesothelioma or by other, less serious conditions.
Mesothelioma that affects the pleura can cause these signs and symptoms:
* chest wall pain
* pleural effusion, or fluid surrounding the lung
* shortness of breath
* fatigue or anemia
* wheezing, hoarseness, or cough
* blood in the sputum (fluid) coughed up (hemoptysis)
In severe cases, the person may have many tumor masses. The individual may develop a pneumothorax, or collapse of the lung. The disease may metastasize, or spread, to other parts of the body.
Tumors that affect the abdominal cavity often do not cause symptoms until they are at a late stage. Symptoms include:
* abdominal pain
* ascites, or an abnormal buildup of fluid in the abdomen
* a mass in the abdomen
* problems with bowel function
* weight loss
In severe cases of the disease, the following signs and symptoms may be present:
* blood clots in the veins, which may cause thrombophlebitis
* disseminated intravascular coagulation, a disorder causing severe bleeding in many body organs
* jaundice, or yellowing of the eyes and skin
* low blood sugar level
* pleural effusion
* pulmonary emboli, or blood clots in the arteries of the lungs
* severe ascites
Symptoms of peritoneal mesothelioma include weight loss and cachexia, abdominal swelling and pain due to ascites (a buildup of fluid in the abdominal cavity). Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.
These symptoms may be caused by mesothelioma or by other, less serious conditions.
Mesothelioma that affects the pleura can cause these signs and symptoms:
* chest wall pain
* pleural effusion, or fluid surrounding the lung
* shortness of breath
* fatigue or anemia
* wheezing, hoarseness, or cough
* blood in the sputum (fluid) coughed up (hemoptysis)
In severe cases, the person may have many tumor masses. The individual may develop a pneumothorax, or collapse of the lung. The disease may metastasize, or spread, to other parts of the body.
Tumors that affect the abdominal cavity often do not cause symptoms until they are at a late stage. Symptoms include:
* abdominal pain
* ascites, or an abnormal buildup of fluid in the abdomen
* a mass in the abdomen
* problems with bowel function
* weight loss
In severe cases of the disease, the following signs and symptoms may be present:
* blood clots in the veins, which may cause thrombophlebitis
* disseminated intravascular coagulation, a disorder causing severe bleeding in many body organs
* jaundice, or yellowing of the eyes and skin
* low blood sugar level
* pleural effusion
* pulmonary emboli, or blood clots in the arteries of the lungs
* severe ascites
MESOTHELIOMA SYMPTOMS
the erliy symptoms of mesothelioma are generally non-specific,and may lead toa delay in diagnosis. sometimes resembling viral pneumonia,pleural mesothelioma patients may present with shortness of breath, chest pain and/or persistent cough; some patients show no symptoms at all. A chest x-ray may show a build-up of fluid or pleural effusion (discussed below). The right lung is affected 60% of the time, with involvement of both lungs being seen in approximately 5% of patients at the time of diagnosis. Less common symptoms of pleural mesothelioma include fever, night sweats and weight loss. Symptoms of peritoneal mesothelioma may include pain or swelling in the abdomen due to a build-up of fluid, nausea, weight loss, bowel obstruction, anemia or swelling of the feet.
PLEASE KEEP IN MIND THAT THESE SYMPTOMS MAY BE CAUSED BY MESOTHELIOMA OR BY OTHER LESS SERIOUS CONDITIONS. ONLY A DOCTOR CAN MAKE A DEFINITIVE DIAGNOSIS.
Information on the symptoms, diagnosis, staging, and treatment of peritoneal mesothelioma.Information on the symptoms, diagnosis, staging, and treatment of pleural mesothelioma.
Pleural EffusionOne of the most common symptoms of mesothelioma is a pleural effusion, or an accumulation of fluid between the parietal pleura (the pleura covering the chest wall and diaphragm) and the visceral pleura (the pleura covering the lungs). Both of these membranes are covered with mesothelial cells which, under normal conditions, produce a small amount of fluid that acts as a lubricant between the chest wall and the lung. Any excess fluid is absorbed by blood and lymph vessels maintaining a balance. When too much fluid forms, the result is an effusion.
TypesPleural effusion is broken down into two categories, transudates and exudates. A transudate is a clear fluid that forms not because the pleural surfaces are diseased, but because of an imbalance between the normal production and removal of the fluid. The most common cause of transudative fluid is congestive heart failure. An exudate, which is often cloudy and contains many cells and proteins, results from disease of the pleura itself, and is common to mesothelioma. To determine whether a fluid is a transudate or exudate, a diagnostic thoracentesis, in which a needle or catheter is used to obtain a fluid sample, may be conducted.
SymptomsAs the volume of fluid increases, shortness of breath, known as "dyspnea", and sometimes pain, ranging from mild to stabbing, may occur. Some patients may experience a dry cough. When the doctor listens to the patient’s chest with a stethoscope, normal breath sounds are muted, and tapping on the chest will reveal dull rather than hollow sounds.
DiagnosisDiagnosis of pleural effusion is usually accomplished with a simple chest x-ray, although CT scans or ultrasound may also be used. A special x-ray technique, called a lateral decubitus film, may be used to detect smaller effusions or to enable the physician to estimate of the amount of fluid present. If the underlying cause of the effusion is readily apparent (such as in the case of severe congestive heart failure), sampling of the fluid may not be necessary, however, because pleural effusion may be symptomatic of a number of disease processes from benign to malignant, a fluid sample is generally taken. Diagnostic thoracentesis, in which cells are extracted from the pleural cavity, is commonly done when the possibility of mesothelioma exists, however, in up to 85% of cases, the fluid tests negative or inconclusive even though cancer is present. It is ultimately a needle biopsy of the pleura (lining of the lung) or an open surgical biopsy which confirms a mesothelioma diagnosis.
TreatmentPleural effusion caused by heart failure or infection can usually be resolved by directing treatment at the cause, however, when testing has realized no diagnosis, and fluid continues to build or recur, doctors may recommend chest tube drainage and chemical pleurodesis. Chemical pleurodesis is a technique in which a sclerosing agent is used to abrade the pleural surfaces producing an adhesion between the parietal and visceral pleurae. This will prevent further effusion by eliminating the pleural space. Talc appears to be the most effective agent for pleurodesis, with a success rate of nearly 95%. It is highly effective when administered by either poudrage or slurry. Poudrage is the most widely used method of instilling talc into the pleural space. Before spraying the talc, the medical team removes all pleural fluid to completely collapse the lung. After the talc is administered, they inspect the pleural cavity to be sure the talc has been evenly distributed over the pleural surface. Some doctors prefer to use talc mixed with saline solution which forms a wet slurry that can roll around the pleural cavity.
Fatigue in Mesothelioma
PatientsMesothelioma Pain
PLEASE KEEP IN MIND THAT THESE SYMPTOMS MAY BE CAUSED BY MESOTHELIOMA OR BY OTHER LESS SERIOUS CONDITIONS. ONLY A DOCTOR CAN MAKE A DEFINITIVE DIAGNOSIS.
Information on the symptoms, diagnosis, staging, and treatment of peritoneal mesothelioma.Information on the symptoms, diagnosis, staging, and treatment of pleural mesothelioma.
Pleural EffusionOne of the most common symptoms of mesothelioma is a pleural effusion, or an accumulation of fluid between the parietal pleura (the pleura covering the chest wall and diaphragm) and the visceral pleura (the pleura covering the lungs). Both of these membranes are covered with mesothelial cells which, under normal conditions, produce a small amount of fluid that acts as a lubricant between the chest wall and the lung. Any excess fluid is absorbed by blood and lymph vessels maintaining a balance. When too much fluid forms, the result is an effusion.
TypesPleural effusion is broken down into two categories, transudates and exudates. A transudate is a clear fluid that forms not because the pleural surfaces are diseased, but because of an imbalance between the normal production and removal of the fluid. The most common cause of transudative fluid is congestive heart failure. An exudate, which is often cloudy and contains many cells and proteins, results from disease of the pleura itself, and is common to mesothelioma. To determine whether a fluid is a transudate or exudate, a diagnostic thoracentesis, in which a needle or catheter is used to obtain a fluid sample, may be conducted.
SymptomsAs the volume of fluid increases, shortness of breath, known as "dyspnea", and sometimes pain, ranging from mild to stabbing, may occur. Some patients may experience a dry cough. When the doctor listens to the patient’s chest with a stethoscope, normal breath sounds are muted, and tapping on the chest will reveal dull rather than hollow sounds.
DiagnosisDiagnosis of pleural effusion is usually accomplished with a simple chest x-ray, although CT scans or ultrasound may also be used. A special x-ray technique, called a lateral decubitus film, may be used to detect smaller effusions or to enable the physician to estimate of the amount of fluid present. If the underlying cause of the effusion is readily apparent (such as in the case of severe congestive heart failure), sampling of the fluid may not be necessary, however, because pleural effusion may be symptomatic of a number of disease processes from benign to malignant, a fluid sample is generally taken. Diagnostic thoracentesis, in which cells are extracted from the pleural cavity, is commonly done when the possibility of mesothelioma exists, however, in up to 85% of cases, the fluid tests negative or inconclusive even though cancer is present. It is ultimately a needle biopsy of the pleura (lining of the lung) or an open surgical biopsy which confirms a mesothelioma diagnosis.
TreatmentPleural effusion caused by heart failure or infection can usually be resolved by directing treatment at the cause, however, when testing has realized no diagnosis, and fluid continues to build or recur, doctors may recommend chest tube drainage and chemical pleurodesis. Chemical pleurodesis is a technique in which a sclerosing agent is used to abrade the pleural surfaces producing an adhesion between the parietal and visceral pleurae. This will prevent further effusion by eliminating the pleural space. Talc appears to be the most effective agent for pleurodesis, with a success rate of nearly 95%. It is highly effective when administered by either poudrage or slurry. Poudrage is the most widely used method of instilling talc into the pleural space. Before spraying the talc, the medical team removes all pleural fluid to completely collapse the lung. After the talc is administered, they inspect the pleural cavity to be sure the talc has been evenly distributed over the pleural surface. Some doctors prefer to use talc mixed with saline solution which forms a wet slurry that can roll around the pleural cavity.
Fatigue in Mesothelioma
PatientsMesothelioma Pain
Subscribe to:
Posts (Atom)